6 BR | 6.5 BA | Sleeps 12 | Dog-Friendly | Heated Plunge Pool | Walk to Beach | House in Isle of Palms

10.0 (7 Reviews) |   Pet Friendly   6 Bedrooms  7 Bathrooms  12 Guests
Isle of Palms House | 6 BR | 6.5 BA | Sleeps 12 | Dog-Friendly | Heated Plunge Pool | Walk to Beach

6 Bedroom House in Isle of Palms

What Up Beach — 26 22nd Avenue, Isle of Palms, SC
Near Beach Luxury Residence with Heated Plunge Pool | Isle of Palms Vacation Rental
Welcome to What Up Beach
This Isle of Palms vacation rental offers elevated coastal living just a short walk from the beach, blending refined interiors with resort-style outdoor amenities. Designed for families and groups, this Charleston beach house features six private king suites, a heated saltwater plunge pool, and thoughtfully curated spaces for gathering and relaxation.
✨ What you’ll love ✨
*6 Bedrooms • 6.5 Bathrooms • Sleeps 12
*Heated saltwater plunge pool (no additional charge)
*~7-minute walk to beach access
*6 king bedrooms with ensuite bathrooms
*Chef’s kitchen with large island seating
*Indoor shuffleboard + two wet bars
*Outdoor lounge with fire table, pizza oven & grill
*Dog-friendly (max 2, fee applies)
*Parking for up to 6 vehicles
🏡 The space
Elegant indoor living
This Charleston beach house is designed for both comfort and connection, featuring a spacious open-concept living area with a plush sectional and large TV. Clean lines, modern finishes, and abundant natural light create a refined yet welcoming coastal atmosphere, ideal for gathering after a day at the beach.
🍽️ Chef’s kitchen & dining
The fully renovated kitchen features stainless steel appliances, generous counter space, and a large island with seating for eight. The adjacent dining area accommodates up to 12 guests, making it easy to host group meals. Two wet bars, each with a mini-fridge, provide added convenience for entertaining.
🛏️ Luxury bedrooms
This Isle of Palms vacation rental offers six king bedrooms, each with a private ensuite bathroom, premium linens, and a flat-screen TV.
• Bedrooms 1–4 (second level): King beds with ensuite baths (select rooms include soaking tubs and double vanities)
• Bedrooms 5–6 (third level): King beds with ensuite baths
This layout provides exceptional privacy and comfort for groups.
🛁 Inspired bathrooms
All six full bathrooms are ensuite, featuring walk-in showers, with select bathrooms offering soaking tubs and double vanities. Four bathrooms include bidets for an elevated experience.
☀️ Outdoor living & views
The outdoor space is designed for relaxed coastal living. Enjoy the heated saltwater plunge pool, unwind by the fire table, or gather around the pizza oven and gas grill for evening meals. A partially covered deck with Adirondack seating offers shade and comfort throughout the day.
🚗 Guest access & parking
Guests have full access to the home, excluding the garage. Parking is available for up to six vehicles in the driveway.
📍 Location
Located just a short 7-minute walk to the beach via 21st or 22nd Avenue, this Isle of Palms vacation rental offers easy access to the shoreline. Nearby, you’ll find local dining, shopping, Harris Teeter, Isle of Palms County Park, and the Recreation Center within a short drive or walk. Historic downtown Charleston is approximately 25 minutes away.
ℹ️ Good to know
• Dog-friendly (maximum 2 dogs, $300 pet fee; no cats permitted)
• No parties or events
• Exterior security cameras in place
• Heated pool included; temperature dependent on weather conditions
🧺 Included with your stay
• High-speed WiFi
• Linens & towels
• Washer & dryer (2 sets)
• Fully stocked kitchen essentials
🌴 The IOP Escapes experience
At IOP Escapes, every stay is thoughtfully curated to deliver a seamless, elevated experience. Our local team is here to ensure your coastal getaway is effortless, memorable, and uniquely yours.
Professional management is provided for this listing by IOP Escapes Vacation Rental
Important notes:
✧ Please be advised that all guests will be asked to sign a rental usage agreement that governs the terms of the stay. By completing the reservation you agree to the following:
✧ You agree to be bound by our rental terms and conditions.
✧ You acknowledge that you may be asked to provide a copy of your official government-issued photo ID, confirm your contact information, provide a valid credit card with a name that matches your ID, and pass through our verification portal and, in some instances, complete a criminal background check. The information is collected for screening and verification only and is not stored or used for any other purposes.
✧ You understand that your check-in instructions might be withheld until you have successfully completed the rental agreement and provided a copy of valid ID.
✧ Any guest who confirms a reservation will be responsible for damages in an amount outlined in the rental agreement. An authorization hold in the amount of $1,500.00 will be placed on your credit card. It will be removed once you check-out and if nothing is damaged.
We are happy to host you for your stay with us! Please keep the following rules in mind during your stay:
1) Local guest reservation requests are subject to further review and questions. Please provide full name, # of guests, and reason for booking.
2) Reservations should include the correct number of guests staying. Please ask the host for permission to bring visitors over to the property.
3) Isle of Palms Noise Ordinance must be followed. Any violations of the noise ordinance are cause for immediate removal.
4) Please be courteous and respectful of the other neighboring residents and guests. Any behavior that results in a complaint by a neighbor, building resident, or HOA is considered violation of this rule.
5) If you have any issues during your stay, please notify us immediately. At check-out please leave the place as you found it upon your arrival. Any costs to repair or replace an item, fixture, or furnishing found damaged after your stay must be compensated by you. All damage and replacement costs include a labor charge.
6) Smoking, Vaping, and Parties of any kind are strictly forbidden.
7) Guests agree to follow the cancellation policy at the time of booking, and agree to any cancellation fee that may apply in the event of a cancellation. Guests agree there are no exceptions to the policy including illness, travel restrictions due to weather, and reasons related to Covid-19. Travel Insurance is offered to cover losses for cancellations during full penalty cancellation period.
10) Guests should inspect the property upon checking-in and notify Management of any issues, damage, missing amenities, or unsatisfactory conditions. Should there be an issue, guests will allow a reasonable amount of time during business hours for Management to address or provide a solution for any reported issues, or unsatisfactory conditions.
11)Pet fee required for all pet friendly rentals
* It is the guests' responsibility to ensure they have all their belongings before checking out. If guests would like an item shipped to them, there is a minimum of $25 shipping and handling fee plus the cost of shipping. We will hold items for 1 week if guests would like to coordinate a pickup of an item.

6 BR | 65 BA | Sleeps 12 | Dog-Friendly | Heated Plunge Pool | Walk to Beach is located in Isle of Palms. 6 BR | 65 BA | Sleeps 12 | Dog-Friendly | Heated Plunge Pool | Walk to Beach provides accommodation, featuring Pool, Balcony/Terrace, Wellness Facilities, among other amenities. This House features Pool, Balcony/Terrace, Wellness Facilities, to make your stay a comfortable one.

6 BR | 65 BA | Sleeps 12 | Dog-Friendly | Heated Plunge Pool | Walk to Beach has 6 Bedrooms , 7 Bathrooms, and max occupancy of 12 people. The minimum rental for this property is 1 nights, but this can change depending on the season you plan on staying. Previous guests have given good rated it, and VRBO labeled it a top-rated House because of the excellent services rendered by the owner or manager of this House, and has consistently provided great experiences for their guests. Most families or guests that use it recommend it to their friends and some of them are repeat guests. House has a friendly neighborhood, and the Isle of Palms has interesting places to visit. If you want to learn more about the House in Isle of Palms, such as places to visit and things to do nearby, you can check below to learn more.

Show more
OneKey Logos

This Property is OneKey Eligible

Earn OneKeyCash for every dollar spent on eligible vacation rentals, villas, cottages, cabins, and more when you book on Vrbo.

JOIN TODAY

Amenities

Air Conditioner
Parking
Pet Friendly
Pool
TV
View
Private Pool
Ocean View
Balcony/Terrace
Oceanfront
Security/Safety
Sports/Activities
Bedding/Linens
Wellness Facilities
Fireplace/Heating
Barbecue/Outdoor Cooking
Child Friendly
Internet
Kitchen
Laundry

Facility Overview

Air Conditioner
  • Air conditioning
  • Heating
Bathrooms
  • Shower
  • Hair dryer
  • 7 bathrooms
  • Towels provided
Bedroom
  • Bed sheets provided
  • 6 bedrooms
  • Dining table
  • Living room
  • Dining room
Kitchen
  • Coffee/tea maker
  • Stovetop
  • Ice maker
  • Kitchen island
  • Dishwasher
  • Cookware/dishes/utensils
  • Toaster
  • Oven
  • Refrigerator
Laundry
  • Laundry facilities
  • Washing machine and dryer
  • Near laundromat
Ocean view
  • Near the beach
Parking
  • Onsite parking
  • Car recommended
Pet Friendly
  • Pet friendly
Accessibility
  • Smoke-free property
Activities
  • Fishing nearby
  • Wildlife and game walks nearby
  • Jet skiing nearby
  • Marina nearby
  • Surfing/body boarding nearby
  • Kayaking nearby
  • Tennis on site
  • Water park
  • Birdwatching nearby
  • Fitness facilities nearby
  • Power boating nearby
  • Ecotours nearby
Entertainment
  • Smart TV
General
  • English
  • Near a hospital
  • Near the bay
  • Near outlet shopping
  • Near the sea
Guest Services
  • Iron/ironing board
Internet
  • Free WiFi
Outdoors
  • Patio
  • Fenced yard
  • Gas grill
Security/Safety
  • Deadbolt lock
  • Carbon monoxide detector installed (host has indicated there is a carbon monoxide detector on the property)
  • Smoke detector installed (host has indicated there is a smoke detector on the property)
  • Fire extinguisher
Spa
  • Private pool

Policies

Check-in
Check-in time starts at 4:00 pm contactless check-in available minimum check-in age: 25
Check-out
Check-out before 10:00 am
Child Policy
Children are welcome.
Event Policy
No events allowed
Pet Policy
Pets allowed service animals are welcome, and are exempt from fees
Smoking Policy
Smoking is not permitted

Extra-person charges may apply and vary depending on property policy government-issued photo identification and a credit card, debit card, or cash deposit may be required at check-in for incidental charges host has indicated there is a carbon monoxide detector on the property host has indicated there is a smoke detector on the property onsite parties or group events are strictly prohibited safety features at this property include a fire extinguisher and a deadbolt lock special requests are subject to availability upon check-in and may incur additional charges; special requests cannot be guaranteed this property is managed through our partner, vrbo. you will receive an email from vrbo with a link to a vrbo account, where you can change or cancel your reservation

Reviews

Bill M.
Oct 16, 2025 09:41:18 AM
Review Score:   10
Summary: Great property, well maintained and close to everything. Easy check in, can’t say anything but good things.
See All Reviews

FAQ's

Is this Isle of Palms house pet-friendly for guests?

Yes, pets are allowed at this property. Check the guest reviews to learn what guests had to share.

Does the Isle of Palms house have a swimming pool?

Yes, this Isle of Palms house has a swimming pool. Check the Facility Overview section for details about the pool and other available facilities.

How much does it cost per night to stay in Isle of Palms house?

Best-rates for the Isle of Palms house starts from $2,678 per night with includes Parking, Sports/Activities, Bedding/Linens, Barbecue/Outdoor Cooking, Child Friendly, Air Conditioner, TV, Ocean View, Oceanfront, Security/Safety, Fireplace/Heating, Kitchen, Pet Friendly, View, Private Pool, Internet, Pool, Balcony/Terrace, Wellness Facilities, Laundry with all other facilities. matches every traveler with their perfect accommodation, whether you are traveling with a group, friends, family, or pets.

Is Isle of Palms house a family-friendly place to stay?

Based on the information we have received from the owner or our partner, this is considered to be a family-friendly property. Families have rated this house Good or guests have recommended them suitable for families. As reported by the owner or manager, the house has specified that children are welcome. Please see details about suitability for your family or inquire with the property to learn more.

Is the Isle of Palms house wheelchair accessible or offer services for disabled guests?

Based on the information received from our partner, the Isle of Palms house has not specified they are wheelchair accessible. Likewise, there is not an elevator specified as being available at the property. Specific accessibility details may be addressed in the property details section of this page.

What is the minimum night stay policy for the Isle of Palms house?

Based on the information reported by the owner or manager, the Isle of Palms house indicates 1 day stay policy at this house. Guests are cautioned that the minimum stay policy may differ based on seasonality or availability and may be at the discretion of the owner or manager.

What cancellation policy is in place for Isle of Palms house?

Guests are cautioned that the cancellation policy may differ based on seasonality, availability, or current travel restrictions. Guests should also be aware that this policy may be subject to change and should be confirmed prior to booking. More details may be available on this page in the property description. However, early check-in or late check-out can sometimes be negotiated between the guest and the owner or the manager of this property.

Check House Availability
Nightly rates from:
USD2,678
You will be redirected to  
Hot Deal - It has been viewed 180 times today
Not the right fit? Check out our other properties in Isle of Palms
Isle of Palms One Bedroom Condo 1/2 block Front Beach fun From US $247
         

10.0 (321 Reviews)
Condo
  • Air Conditioner
  • Parking
  • Pet Friendly
Fairway Dunes 14 From US $250
         

|
10.0 (1 Review)
House
  • Air Conditioner
  • Parking
  • Pool
513 Seascape by AvantStay From US $271
         

|
10.0 (5 Reviews)
House
  • Air Conditioner
  • Parking
  • Pool
#109 Heart of IOP 1st Fl Studio 4 Min Walk 2 Beach From US $267
         

10.0 (126 Reviews)
Condo
  • Air Conditioner
  • Parking
  • Pet Friendly
30 22nd Ave From US $298
         

|
10.0 (4 Reviews)
House
  • Air Conditioner
  • Parking
  • View
#202 "Top O' the Stairs" 2Br/1Ba, Pet-Friendly From US $327
         

10.0 (45 Reviews)
Condo
  • Air Conditioner
  • Parking
  • Pet Friendly
SG8A: 8A Seagrove Villa From US $260
         

|
10.0 (4 Reviews)
House
  • Pool
  • View
  • Security/Safety
Easy Breezy 2 Bd, 1st Floor, 4 Min to Beach From US $320
         

10.0 (44 Reviews)
Condo
  • Air Conditioner
  • Parking
  • Pet Friendly
3 bed/3 Bath with Amazing Views! Sleeps 8 From US $636
         

9.8 (176 Reviews)
Condo
  • Air Conditioner
  • Parking
  • Pool
Port O' Call E303 by Deserving Vacations From US $491
         

9.8 (144 Reviews)
Villa
  • Air Conditioner
  • Parking
  • Pool
High Life on IOP Studio + Sleeper,1 blk to beach, From US $269
         

10.0 (99 Reviews)
Condo
  • Air Conditioner
  • Parking
  • Pet Friendly
Port O' Call D101 by Deserving Vacations From US $414
         

9.6 (92 Reviews)
Villa
  • Air Conditioner
  • Parking
  • Pool
'Belle Mer'~ OCEAN FRONT, PRIVATE POOL, HOT TUB, ELEVATOR From US $4,412
         

Beautiful Pet Friendly Beach House with Private Backyard Oasis. From US $609